A Growth Curve Model of Learning Acquisition among Cognitively Normal Older Adults
نویسندگان
چکیده
منابع مشابه
Exercise and Alzheimer's disease biomarkers in cognitively normal older adults.
OBJECTIVE In addition to the increasingly recognized role of physical exercise in maintaining cognition, exercise may influence Alzheimer's disease (AD) pathology, as transgenic mouse studies show lowered levels of AD pathology in exercise groups. The objective of this study was to elucidate the association between exercise and AD pathology in humans using Pittsburgh compound-B (PIB), amyloid-b...
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OBJECTIVES To examine the relationship between key functional impairments, co-morbid conditions and driving performance in a sample of cognitively normal older adults. DESIGN Prospective observational study. SETTING The Knight Alzheimer's Disease Research Center, Washington University at St. Louis. PARTICIPANTS Individuals with normal cognition, 64.9 to 88.2 years old (N = 129), with a va...
متن کاملAmyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults.
Normal aging is often difficult to distinguish from the earliest stages of Alzheimer's disease. Years before clinical memory deficits manifest, amyloid-β deposits in the cortex in many older individuals. Neuroimaging studies indicate that a set of densely connected neocortical regions, referred to as the default network, is especially vulnerable to amyloid-β deposition. Yet, the impact of amylo...
متن کاملAssessing pain in cognitively impaired older adults.
BACKGROUND Accurate assessments of pain help healthcare professionals to identify its source and manage it appropriately. Pain in cognitively impaired older adults is difficult to assess and this can result in poor management and outcomes. In response to the vulnerability of this patient group, researchers have produced a variety of tools for pain assessment in cognitively impaired older adults...
متن کاملCognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis
INTRODUCTION This meta-analysis aimed to characterize the nature and magnitude of amyloid (Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals. METHOD MEDLINE Ovid was searched from 2012 to June 2016 for studies reporting relationships between cerebrospinal fluid or positron emission tomography (PET) Aβ levels and cognitive impairment (cross-sectional) an...
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ژورنال
عنوان ژورنال: Experimental Aging Research
سال: 2005
ISSN: 0361-073X,1096-4657
DOI: 10.1080/03610730590948195